[1]王志锋,高鸿英,于武高.芪花生肌胶囊的质量标准研究[J].甘肃中医药大学学报,2011,(05):42-45.
 Wang Zhifeng,Gao Hongying,Yu Wugao.Study of quality standard of Qihua Shengji Capsule[J].Journal of Gansu University of Chinese Medicine,2011,(05):42-45.
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芪花生肌胶囊的质量标准研究()
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《甘肃中医药大学学报》[ISSN:1003-8450/CN:62-1062/R]

卷:
期数:
2011年05期
页码:
42-45
栏目:
中药研究
出版日期:
1900-01-01

文章信息/Info

Title:
Study of quality standard of Qihua Shengji Capsule
作者:
王志锋1 高鸿英2 于武高1
1. 甘肃新兰药药业有限公司, 甘肃 兰州 730046;
2. 兰州大得利生物化学制药有限公司, 甘肃 兰州 730046
Author(s):
Wang Zhifeng1 Gao Hongying2 Yu Wugao1
1. Gansu Pharmaceutical Limited Company of Xinlan Medicine, Lanzhou 730046, China;
2. Lanzhou Dadeli Limited Company of Biochemical Pharmaceutical, Lanzhou 730046, China
关键词:
芪花生肌胶囊质量标准TLCHPLC黄芪甲苷
Keywords:
Qihua shengji Capsulequality standardTLCHPLCastragaloside
分类号:
R284.1
摘要:
目的 制订芪花生肌胶囊的质量控制方法。方法 采用薄层色谱法(TLC)对芪花生肌胶囊方中当归、金银花进行鉴别, 采用高效液相色谱法(HPLC)测定芪花生肌胶囊中黄芪甲苷的含量。结果 TLC鉴别方法专属性强;黄芪甲苷线性范围为0.996~9.960 μg(r=0.999 8), 平均回收率为97.90%, RSD为1.77% (n=6)。结论 本方法操作简便, 结果准确, 灵敏度高, 重复性好。该质量标准可有效地控制芪花生肌胶囊的质量。
Abstract:
Objective To consummate a method for quality control of Qihua shengji Capsule. Methods TLC was used for the identification of Angelica sinensis and Lonicera japonica, and HPLC was used for the determination of astragaloside in Qihua shengji Capsule. Results The TLC identification method was highly specific and the spots were clear. The linear range of astragaloside was from 0.996 to 9.960 μg (r=0.999 8). The average recovery of astragaloside was 97.9%, RSD was 1.77% (n=6). Conclusion The method is easy to operate with accurate results, high sensitivity and good reproducibility. The quality standard can effectively control the quality of Qihua shengji Capsule.

参考文献/References:

[1] 国家药典委员会.中华人民共和国药典(一部)[M].北京:化学工业出版社, 2010:124-125, 205-206, 283-284.
[2] 伍丕娥, 周娟, 徐廷泽, 等.喉泰喷雾剂的薄层鉴别[J].华西药学杂志, 2003, 18(4):294-295.
[3] 兰丙欣, 余孝东, 尹秋霞.薄层扫描法测定益肾抗衰片中黄芪甲苷的含量[J].中国药房, 2003, 14(3):173-174.
[4] 杨春欣, 孙丽霞, 许根英.薄层色谱-分光光度法测定黄芪粉针剂中黄芪甲苷的含量[J].中草药, 2001, 32(4):312-314.
[5] 郑国华, 冯其麟, 陈求房, 等.高效液相色谱-蒸发光散射检测器法测定复方甲亢片黄芪甲甙含量[J].医药导报, 2008, 27(11):1398-1399.

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备注/Memo

备注/Memo:
收稿日期:2011-04-01
作者简介:王志锋(1976-),男,工程师,理学学士。研究方向:中药质量标准及复方中药新药研究。
更新日期/Last Update: 1900-01-01