[1]高春燕,林逸,华洁,等.中医干预联合玻璃酸钠关节腔注射治疗膝关节骨性关节炎45例临床观察[J].甘肃中医药大学学报,2015,32(06):32-35.
 GAO Chunyan,LIN Yi,HUA Jie,et al.Clinical observation of TCM therapy plus sodium hydaluronate intraarticular injection in treating 45 cases of knee osteoarthritis[J].Journal of Gansu University of Chinese Medicine,2015,32(06):32-35.
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中医干预联合玻璃酸钠关节腔注射治疗膝关节骨性关节炎45例临床观察()
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《甘肃中医药大学学报》[ISSN:1003-8450/CN:62-1062/R]

卷:
32卷
期数:
2015年06期
页码:
32-35
栏目:
临床研究与报道
出版日期:
2015-12-25

文章信息/Info

Title:
Clinical observation of TCM therapy plus sodium hydaluronate intraarticular injection in treating 45 cases of knee osteoarthritis
作者:
高春燕13 林逸1 华洁1 童培建2
1. 浙江中医药大学第一临床医学院, 浙江杭州 310053;
2. 浙江省中医院骨伤科, 浙江杭州 310007;
3. 浙江省骨伤研究所, 浙江杭州 310053
Author(s):
GAO Chunyan13 LIN Yi1 HUA Jie1 TONG Peijian2
1. The First Clinical Medicine School, Zhejiang University of Chinese Medicine, Hangzhou 310053, China;
2. Orthopedics and Traumatology Department, Zhejiang TCM Hospital, Hangzhou 310007, China;
3. Zhejiang Institute of Orthopedics and Traumatology,
关键词:
膝关节骨性关节炎中医疗法玻璃酸钠关节腔注射临床观察
Keywords:
knee osteoarthritis (KOA)TCM therapysodium hydaluronateintraarticular injectionclinical observation
分类号:
R274.943
摘要:
目的观察中医干预联合玻璃酸钠关节腔注射治疗膝关节骨性关节炎(KOA)的临床疗效。方法将135例KOA患者采用随机数字表法分为治疗组、中医干预组和玻璃酸钠组,每组45例。治疗组给予自拟中药方内服及自制膏药加用展筋活血散局部外敷的同时,行玻璃酸钠膝关节腔注射治疗,余2组分别单独给予中医干预治疗和玻璃酸钠关节腔注射治疗。治疗5周后根据加拿大西安大略和麦克马斯特大学(简称WOMAC)骨关节炎指数评分、视觉模拟评分(简称VAS)及相关校准进行疗效评价。结果治疗组总有效率为95.56%,显著高于中医干预组的84.44%和玻璃酸钠组的88.89%,差异有统计意义(P<0.05)。3组患者治疗后膝关节WOMAC和VAS评分较同组治疗前均显著降低,且治疗后,治疗组的膝关节WOMAC评分显著低于中医干预组和玻璃酸钠组,差异均有统计意义(P<0.05)。治疗后,中医干预组和玻璃酸钠组WOMAC和VAS评分比较,差异均无统计意义(P>0.05)。结论中医干预联合玻璃酸钠关节腔注射综合治疗KOA,其疗效优于单纯中医干预治疗及玻璃酸钠注射治疗,可有效缓解关节疼痛,改善关节功能,提高患者生活质量。
Abstract:
Objective To observe the clinical efficacy of TCM therapy plus sodium hydaluronate intraarticular injection in treating knee osteoarthritis (KOA). Methods 135 cases were randomly divided into treatment group,TCM group and sodium hydaluronate group. The treatment group was treated with sodium hydaluronate intraarticular injection plus internal and external application of self-made Chinese medicine. The other two groups were intervened by TCM therapy and sodium hydaluronate injection individually. On 5th week after treatment,therapeutic evaluation was made based on the scores of WOMAC and VAS. Results The total effective rate of treatment group was 95.56%,much higher than that of other 2 groups (84.44%,88.89%),there was a significant difference (P<0.05). After treatment,the scores of WOMAC and VAS of 3 groups decreased obviously,the treatment group was the most predominant,the difference was significant (P<0.05). Additionally,there was no any significance in comparing the scores of TCM group and sodium hydaluronate group (P>0.05). Conclusion The combined treatment is superior to other single therapy. It is effective in relieving the pain,improving the function of joint and bettering the quality of living for the patients.

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备注/Memo

备注/Memo:
收稿日期:2015-03-03
基金项目:国家自然科学基金青年项目(81202710);中国博士后科学基金(81202710);十二五重大科技专项(2012C13017-2);浙江省重点科技创新团队计划资助(2011R50022);浙江省重点实验室计划资助(2013E10024)。
作者简介:高春燕(1991-),女,在读硕士研究生。研究方向:干细胞治疗股骨头坏死。
通信作者:童培建(1961-),男,主任医师,教授,医学博士,主要从事干细胞治疗股骨头坏死,微创关节置换,肝移植术后关节置
更新日期/Last Update: 1900-01-01