[1]李民,贺鑫,林哲辉,等.疯痹贴治疗膝骨性关节炎风寒湿痹证临床观察[J].甘肃中医药大学学报,2016,33(06):62-65.[doi:10.16841/j.issn1003-8450.2016.06.19]
 LI Min,HE Xin,LIN Zhehui,et al.Clinical observation of curative effect on knee osteoarthritis treated with Fengbi Tie[J].Journal of Gansu University of Chinese Medicine,2016,33(06):62-65.[doi:10.16841/j.issn1003-8450.2016.06.19]
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疯痹贴治疗膝骨性关节炎风寒湿痹证临床观察()
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《甘肃中医药大学学报》[ISSN:1003-8450/CN:62-1062/R]

卷:
33卷
期数:
2016年06期
页码:
62-65
栏目:
临床研究与报道
出版日期:
2016-12-25

文章信息/Info

Title:
Clinical observation of curative effect on knee osteoarthritis treated with Fengbi Tie
作者:
李民1 贺鑫2 林哲辉3 林若曦4
1. 福建中医药大学附属康复医院骨伤康复科, 福建 福州 350003;
2. 福建中医药大学中西医结合学院, 福建 福州 350122;
3. 福建中医药大学附属漳州市中医院骨伤科, 福建 漳州 363000;
4. 美国马里兰州巴尔的摩市联合纪念医院内科, 马里兰州 巴尔的摩 21202
Author(s):
LI Min1 HE Xin2 LIN Zhehui3 LIN Ruoxi4
1. Orthopedic Rehabilitation Department, Fujian Rehabilitation Hospital Affiliated to Fujian University of TCM, Fuzhou, Fujian, 350003, China;
2. College of Chinese and Western Integrative Medicine, Fujian University of TCM, Fuzhou, Fujian, 350122, Chi
关键词:
膝骨性关节炎风寒湿痹证中医药疗法疯痹贴传统剂型改良剂型临床观察
Keywords:
knee osteoarthritisarthralgia due to wind-cold-dampnesstraditional medicinal treatmentFengbi Patchconventional dosage formmodification of dosage formclinical observation
分类号:
R255.6
DOI:
10.16841/j.issn1003-8450.2016.06.19
摘要:
目的 观察疯痹贴传统剂型和改良剂型治疗膝骨性关节炎(KOA)风寒湿痹证的临床疗效及其致敏作用。方法 将符合纳入标准的111例KOA风寒湿痹证患者随机分为3组,每组37例。试验A组、试验B组分别采用疯痹贴传统剂型及疯痹贴改良剂型敷贴在膝关节部位(以髌骨为中心),1贴/3 d,间隔1 d,连续治疗1月;对照组予双氯芬酸二乙胺(扶他林)乳胶剂局部外涂于患处,3次/d,连续治疗1月。分别在治疗前、后及治疗结束3月后随访时,记录患者的视觉模拟评分法(VAS)评分及Lequesne指数评分。结果 3组治疗后及治疗结束3月后膝关节VAS评分、Lequesne指数评分均显著降低,与同组治疗前比较,差异均有统计意义(P<0.05或P<0.01),且试验A组和试验B组Lequesne指数评分降低幅度显著大于对照组(P<0.05或P<0.01)。结论 疯痹贴传统剂型及其改良剂型治疗KOA风寒湿痹证疗效优于双氯芬酸二乙胺乳胶剂;疯痹贴改良剂型治疗KOA风寒湿痹证与疯痹帖传统剂型比较疗效相当,但疯痹贴改良剂型不良反应小于传统剂型。
Abstract:
Objective To observe the sensitization effect and curative effect on knee osteoarthritis with Fengbi Patch and its modifications. Methods 111 clinic patients that fit inclusion criteria were randomly divided into experiment group A,B and control group,37 cases each. Patches were placed in knee joint (take kneecap as central position) in group A (conventional dosage form) and B (modification of dosage form),1 patch for 3 days,one day apart,one month as a course. Diolofenac diethylamine emulgel was locally administrated in control group continuously for a month (3 times a day). The scores of visual analogue scale (VAS) and Lequesne index were recorded before treatment,while finishing treatment and during follow up 3 months after treatment. Results Scores of VAS and Lequesne index in 3 groups decreased while finishing treatment and during follow up 3 months after treatment. Compared with that of before treatment,the difference was significant (P<0.05 or P<0.01). The reductions in group A and B were more evident than that in control group (P<0.05 or P<0.01). Conclusion The curative effect of Fengbi Patch and its modification on knee osteoarthritis is better than that of diolofenac diethylamine emulgel; the curative effect of the modification of Fengbi Patch on knee osteoarthritis is equal to that of its convenional type with less adverse reaction.

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备注/Memo

备注/Memo:
收稿日期:2015-12-29
基金项目:福建漳州市科技局项目(zz2013j38)。
作者简介:李民(1973-),男,副主任医师,医学博士,主要从事老年性骨关节病的研究。
更新日期/Last Update: 1900-01-01