[1]黄奚,令狐庆.仙方活命饮对低位肛周脓肿一期根治术后创面促愈作用的临床研究[J].甘肃中医药大学学报,2017,34(03):52-56.[doi:10.16841/j.issn1003-8450.2017.03.14]
 HUANG Xi,LINGHU Qing.Curative study of Xianfang Huoming Yin in wound healing after primary radical surgery for low perianal abscess[J].Journal of Gansu University of Chinese Medicine,2017,34(03):52-56.[doi:10.16841/j.issn1003-8450.2017.03.14]
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仙方活命饮对低位肛周脓肿一期根治术后创面促愈作用的临床研究()
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《甘肃中医药大学学报》[ISSN:1003-8450/CN:62-1062/R]

卷:
34卷
期数:
2017年03期
页码:
52-56
栏目:
临床研究与报道
出版日期:
2017-06-25

文章信息/Info

Title:
Curative study of Xianfang Huoming Yin in wound healing after primary radical surgery for low perianal abscess
作者:
黄奚 令狐庆
徐州市中医院肛肠科, 江苏 徐州 221000
Author(s):
HUANG Xi LINGHU Qing
Anorectal Section, Xuzhou TCM Hospital, Xuzhou, Jiangsu, 221000, China
关键词:
低位肛周脓肿一期根治术创面愈合仙方活命饮临床观察
Keywords:
low perianal abscessprimary radical surgerywound healingXianfang Huoming Yinclinical observation
分类号:
R266
DOI:
10.16841/j.issn1003-8450.2017.03.14
摘要:
目的 观察仙方活命饮促进低位肛周脓肿患者一期根治术后创面愈合的临床疗效。方法 选取80例低位肛周脓肿患者作为研究对象,并随机分为治疗组和对照组,各40例。2组均予一期根治术治疗,术后治疗组给予仙方活命饮口服,对照组给予抗生素静脉滴注,2组均给药7 d。比较2组患者的创面愈合时间、肉芽生长情况评分、创面愈合率、血白细胞(WBC)、中性粒细胞比率(N%)及血清人表皮生长因子(EGF)含量。结果 治疗组创面愈合时间为(23.73±2.75) d,对照组为(29.24±2.97) d,2组比较差异有统计学意义(P<0.05);治疗组术后第7天、15天创面愈合率显著高于对照组,差异均有统计学意义(P<0.05);治疗组术后第7天、15天肉芽组织生长情况评分显著低于对照组,差异均有统计学意义(P<0.05);2组术后第3天、7天血WBC及N%与同组术前比较显著降低,差异均有统计学意义(P<0.05或P<0.01),但与对照组比较差异均无统计学意义(P>0.05);治疗组术后第7天、15天血清EGF含量显著高于对照组,差异均有统计学意义(P<0.05)。结论 仙方活命饮能促进低位肛周脓肿一期根治术后创面的愈合,在抑制炎症方面与合理、正规地使用抗生素无明显差异。
Abstract:
Objective To observe the clinical efficacy of Xianfang Huoming Yin in healing the wound after primary radical surgery for low perianal abscess. Methods 80 patients with low perianal abscess were randomly divided into treatment group and control group,40 cases each group. After primary radical surgery for all patents,the treatment group took Xianfang Huoming Yin orally while the control group was intervened with intravenous drip of antibiotics,all for 7 days. Time of wound healing,growth of granulation tissue grading,wound healing rate,WBC,neutrophile granulocyte and the content of serum EGF were compared. Results Time of wound healing in treatment group and control group were (23.73±2.75) d and (29.24±2.97) d respectively,the difference was statistically significant (P<0.05);wound healing rates on 7th day and 15th day in treatment group were much higher than that in control group,there was a significant difference (P<0.05);score on the growth of granulation tissue in treatment group was lower than that in control group,the difference was significant (P<0.05);WBC and neutrophile granulocyte on 3rd day and 7th day after surgery reduced more than before in both groups,the differences were signi-ficant (P<0.05 or P<0.01),but no difference on group comparison (P>0.05);content of serum EGF of treatment group on 7th day and 15th day after surgery was much higher than that of control group,the difference was significant (P<0.05). Conclusion Xianfang Huoming Yin can improve the wound healing in patients with low perianal abscess after surgery to some extent. In inhibiting inflammation,Xianfang Huoming Yin has the same effect as rational usage of antibiotics.

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备注/Memo

备注/Memo:
收稿日期:2016-08-17。
作者简介:黄奚(1985-),女,主治医师,医学硕士,主要从事中医肛肠病的临床治疗。
通信作者:令狐庆(1959-),女,主任医师,硕士生导师,医学学士,主要从事中医肛肠的临床与教学研究。E-mail:13852000869@163.com
更新日期/Last Update: 1900-01-01