[1]麻志恒,施志琴,张汉新,等.抗纤灵汤治疗血瘀型慢性肾功能衰竭34例临床观察[J].甘肃中医药大学学报,2017,34(06):44-47.[doi:10.16841/j.issn1003-8450.2017.06.13]
 MA Zhiheng,SHI Zhiqin,ZHNAG Hanxin,et al.Clinical observation of Kangxianling Tang in treating chronic renal failure due to blood stasis on 34 cases patients[J].Journal of Gansu University of Chinese Medicine,2017,34(06):44-47.[doi:10.16841/j.issn1003-8450.2017.06.13]
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抗纤灵汤治疗血瘀型慢性肾功能衰竭34例临床观察()
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《甘肃中医药大学学报》[ISSN:1003-8450/CN:62-1062/R]

卷:
34卷
期数:
2017年06期
页码:
44-47
栏目:
临床研究与报道
出版日期:
2017-12-25

文章信息/Info

Title:
Clinical observation of Kangxianling Tang in treating chronic renal failure due to blood stasis on 34 cases patients
作者:
麻志恒1 施志琴1 张汉新1 高志生1 何立群2
1. 上海交通大学医学院附属新华医院崇明分院中医内科, 上海 202150;
2. 上海中医药大学附属曙光医院肾病科, 上海 201203
Author(s):
MA Zhiheng1 SHI Zhiqin1 ZHNAG Hanxin1 GAO Zhisheng1 HE Liqun2
1. Xinhua Hospital Chongming Branch Affiliated to Medicine School of Shanghai Jiaotong University, Shanghai, 202150, China;
2. Nephropathy Department, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 201203
关键词:
慢性肾功能衰竭血瘀型抗纤灵汤半胱氨酸蛋白酶抑制物C同型半胱氨酸临床观察
Keywords:
chronic renal failureblood stasisKangxianling TangCysCHcyclinical observation
分类号:
R256.6
DOI:
10.16841/j.issn1003-8450.2017.06.13
摘要:
目的 观察抗纤灵汤治疗血瘀型慢性肾功能衰竭(CRF)的临床疗效。方法 将64例血瘀型CRF患者随机分为治疗组34例和对照组30例。2组均给予基础治疗,对照组在基础治疗的基础上口服氯沙坦,治疗组在基础治疗的基础上口服抗纤灵汤。2组均以8周为1个疗程,1个疗程后比较2组治疗前后血清肌酐(Scr)、尿素氮(BUN)、半胱氨酸蛋白酶抑制物C (CysC)、β2-微球蛋白(β2-MG)、同型半胱氨酸(Hcy)含量及临床疗效。结果 治疗组总有效率为88.2%,对照组为73.3%,2组比较差异有统计学意义(P<0.05);2组治疗后血清Scr,BUN,β2-MG,CysC,Hcy含量均显著低于同组治疗前,差异有统计学意义(P<0.05或P<0.01),治疗后治疗组血清Scr,BUN,β2-MG,CysC,Hcy含量均显著低于对照组,2组比较差异有统计学意义(P<0.05或P<0.01)。结论 抗纤灵汤能降低血瘀型CRF患者血清Scr,BUN,β2-MG,CysC,Hcy含量,且临床疗效显著,值得临床推广应用。
Abstract:
Objective To observe the clinical effect of Kangxianling Tang to the chronic renal failure (CRF) due to blood stasis in patients. Methods 64 patients of chronic renal failure were divided into control group (30 cases) and treatment group (34 cases) randomly. Besides primary treatment in each,the control group took losartan orally and the treatment group was given Kangxianling Tang additionally. After one course (8 weeks),the contents of Scr,BUN,CysC,β2-MG,CysC and Hcy were measured as well as the clinical efficacy were compared. Results The total effective rates in control group and treatment group were 73.3% and 88.2% respectively,the difference was significant (P<0.05);the contents of Scr,BUN,β2-MG,CysC,Hcy in two groups were much lower than that before treatment,there were differences (P<0.05 or P<0.01),while the contents in treament group decreased much more,there were differences between two groups (P<0.05 or P<0.01). Conclusion The decoction of Kangxianling Tang has an evident curative effect in treating chronic renal failure patients and it is worthy of clinical promotion and application.

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备注/Memo

备注/Memo:
收稿日期:2016-09-26。
基金项目:上海市崇明县科委课题资助项目(CKY204-01)。
作者简介:麻志恒(1976-),男,副主任医师,在读博士研究生,主要从事中西医防治肾脏病的临床及实验研究工作。
通信作者:何立群(1959-),男,主任医师,教授,博士生导师,博士后合作导师,医学博士,主要从事肾脏病的基础及临床研究工作。E-mail:liqunhe59@163.com
更新日期/Last Update: 1900-01-01