[1]袁香坤,孙云川,何新颖,等.自拟紫草如意金黄组方外敷联合氧喷治疗急性放射性皮肤损伤30例临床观察[J].甘肃中医药大学学报,2017,34(06):62-66.[doi:10.16841/j.issn1003-8450.2017.06.18]
 YUAN Xiangkun,SUN Yunchuan,HE Xinyin,et al.Clinial study on external application of self-prescribed Zicao Ruyi Jinhuang recipe combined with oxygen injection in treating 30 patients with acute radiation injury of skin[J].Journal of Gansu University of Chinese Medicine,2017,34(06):62-66.[doi:10.16841/j.issn1003-8450.2017.06.18]
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自拟紫草如意金黄组方外敷联合氧喷治疗急性放射性皮肤损伤30例临床观察()
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《甘肃中医药大学学报》[ISSN:1003-8450/CN:62-1062/R]

卷:
34卷
期数:
2017年06期
页码:
62-66
栏目:
临床研究与报道
出版日期:
2017-12-25

文章信息/Info

Title:
Clinial study on external application of self-prescribed Zicao Ruyi Jinhuang recipe combined with oxygen injection in treating 30 patients with acute radiation injury of skin
作者:
袁香坤 孙云川 何新颖 左晓娜 谢昱伟 黄如敬 郭剑非
沧州中西医结合医院放疗科, 河北 沧州 061000
Author(s):
YUAN Xiangkun SUN Yunchuan HE Xinyin ZUO Xiaona XIE Yuwei HUANG Rujing GUO Jianfei
Radiaotherapy Department, Cangzhou Integrated Traditional Chinese and Western Medicine Hospital, Cangzhou, Hebei, 061000, China
关键词:
放射性皮肤损伤紫草如意金黄组方氧喷喜辽妥临床观察
Keywords:
radiation injury of skinZicao Ruyi Jinhuang recipeoxygen injectionXiliaotuoclinical observation
分类号:
R268
DOI:
10.16841/j.issn1003-8450.2017.06.18
摘要:
目的 观察自拟紫草如意金黄组方外敷联合氧喷治疗急性放射性皮肤损伤的临床疗效。方法 将120例Ⅱ级、Ⅲ级急性放射性皮肤损伤患者随机分为A,B,C,D 4组,各30例。A组皮肤损伤处给予自拟紫草如意金黄组方外敷治疗,B组给予自拟紫草如意金黄组方外敷联合氧喷治疗,C组给予喜疗妥外敷治疗,D组给予喜疗妥外敷联合氧喷治疗。4组均连续治疗15 d后比较临床疗效、创面愈合时间及生存质量疗效。结果 治疗后A,B,C,D组临床疗效总有效率分别为70.0%,93.4%,66.7%,90.0%,B,D组与A,C组比较,差异有统计学意义(P<0.01);治疗后B,D组创面愈合时间明显缩短,B,D组与A,C组比较,差异有统计学意义(P<0.05);治疗后A,B,C,D组生存质量疗效总有效率分别为56.7%,90.0%,53.3%,86.7%,B,D组与A,C组比较,差异有统计学意义(P<0.01)。结论 自拟紫草如意金黄组方外敷联合氧喷能有效缩短急性放射性皮肤损伤患者的创面愈合时间,提高临床疗效,值得临床推广。
Abstract:
Objective To observe the clinical efficacy of external application of self-prescribed Zicao Ruyi Jinhuang recipe combined with oxygen injection in treating patients with acute radiation injury of skin.Methods 120 patients with acute radiation injury of skin (degreeⅡand degree Ⅲ) were randomly divided into group A,group B,group C and group D,30 cases in each group.Group A was treated with external application of self-prescribed Zicao Ruyi Jinhuang recipe;group B was given external application of self-prescribed Zicao Ruyi Jinhuang recipe combined with oxygen injection;group C was treated with external application of Xiliaotuo (German,Produktions GmbH);group D was given external application of Xiliaotuo combined with oxygen injection.On 15th day after successive treatment,clinical efficacy,wound healing time and quality of life were compared and analyzed among 4 groups.Results The total clinical effective rates of group A,B,C,D were 70.0%,93.4%,66.7% and 90.0% respectively,there was a difference between group B,D and group A,C (P<0.01);wound healing time in group B and D were much shorter than that in group A and C,the difference was significant (P<0.05);after treatment,total effective rates of quality life in 4 groups were 56.7%,90.0%,53.3% and 86.7% respectively,comparison between group B,D and group A,C had a significant difference (P<0.01).Conclusion The combined therapy is effective in shortening the wound healing time for the patients with acute radiation injury of skin and improves the efficacy.It deserves further clinical application.

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相似文献/References:

[1]丁繁,王小虎,单晓梅.金黄散对肿瘤患者放射性皮肤损伤的疗效观察[J].甘肃中医药大学学报,2013,(01):22.

备注/Memo

备注/Memo:
收稿日期:2016-12-12。
基金项目:河北省中医药管理局科研计划项目(2014353)。
作者简介:袁香坤(1973-),女,副主任医师,医学学士,主要从事肿瘤放射治疗学的临床与科研工作。
通信作者:孙云川(1973-),男,主任医师,医学学士,主要从事肿瘤放射治疗学的临床与科研工作。E-mail:13932719095@163.com
更新日期/Last Update: 1900-01-01