[1]宋凡君,张邵婕,肖斌,等.盐酸氨酮戊酸散光动力疗法治疗中、重度痤疮30例临床观察[J].甘肃中医药大学学报,2018,35(02):62-65.[doi:10.16841/j.issn1003-8450.2018.02.17]
 SONG Fanjun,ZHANG Shaojie,XIAO Bin,et al.Clinical observation on 30 cases of moderate and severe acne treated with aminolevulinic acid photodynamic therapy[J].Journal of Gansu University of Chinese Medicine,2018,35(02):62-65.[doi:10.16841/j.issn1003-8450.2018.02.17]
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盐酸氨酮戊酸散光动力疗法治疗中、重度痤疮30例临床观察()
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《甘肃中医药大学学报》[ISSN:1003-8450/CN:62-1062/R]

卷:
35卷
期数:
2018年02期
页码:
62-65
栏目:
临床研究与报道
出版日期:
2018-04-25

文章信息/Info

Title:
Clinical observation on 30 cases of moderate and severe acne treated with aminolevulinic acid photodynamic therapy
作者:
宋凡君1 张邵婕1 肖斌1 崔树婷1 杨桂兰2 陈敬德3
1. 甘肃中医药大学临床医学院, 甘肃 兰州 730000;
2. 兰州军区兰州总医院皮肤科, 甘肃 兰州 730050;
3. 酒泉市人民医院皮肤科, 甘肃 酒泉 735000
Author(s):
SONG Fanjun1 ZHANG Shaojie1 XIAO Bin1 CUI Shuting1 YANG Guilan2 CHEN Jingde3
1. College of Clinical Medicine, Gansu University of Chinese Medicine, Lanzhou, Gansu, 730000, China;
2. Department of Dermatology, Hospital of Lanzhou Military Region, Lanzhou, Gansu, 730050, China;
3. Department of Dermatology, the People’s Hospital in Jiuquan, Jiuquan, Gansu, 735000, China
关键词:
痤疮盐酸氨酮戊酸散光动力疗法中药面膜临床观察
Keywords:
acneALA-PDTTCM facial maskclinical observation
分类号:
R758.73+3
DOI:
10.16841/j.issn1003-8450.2018.02.17
摘要:
目的 观察盐酸氨酮戊酸散光动力疗法(ALA-PDT)治疗中、重度痤疮的临床疗效。方法 将60例中、重度痤疮患者随机分为治疗组和对照组,各30例。2组均给予常规治疗,治疗组在常规治疗的基础上给予ALA-PDT治疗,20 min/次,2周1次,3次为1个疗程;对照组在常规治疗的基础上给予自制中药面膜外敷,20 min/次,1周1次,6次为1个疗程。分别于治疗第2,4,6周后比较2组的临床疗效,治疗结束后比较2组的不良反应发生情况。结果 治疗后第2,4,6周对照组总有效率分别为76.7%,86.6%,93.3%,治疗组分别为86.6%,93.3%,100.0%,同期组间比较差异均有统计学意义(P<0.05);治疗组总不良反应发生率为26.7%,对照组为13.3%,2组比较差异无统计学意义(χ2=0.677,P>0.05)。结论 ALA-PDT是临床中治疗中、重度痤疮安全、有效的方法。
Abstract:
Objective To observe the clinical effect of moderate and severe acne treated with aminolevulinic acid photodynamic therapy (ALA-PDT). Methods 60 cases of patients with moderate and severe acne were randomly divided into treatment group and control group with 30 cases in each,they were both given routine therapy. Then,the treatment group was given ALA-PDT based on the routine therapy,each time for 20 minutes,once 2 weeks,and 3 times as one course. The control group was given external application of self-made TCM facial mask based on the routine therapy,each time for 20 minutes,once 1 week,and 6 times as one course.The clinical effects of two groups were compared at 2nd,4th and 6th week.After treatment,the adverse effects in two groups were observed and compared.Results The total effective rates at 2nd,4th and 6th week were 76.7%,86.6% and 93.3% in control group and 86.6%,93.3%,100.0% in treatment group,the difference was statistically significant(P<0.05).The adverse effect rates were 26.7% in treatment group and 13.3% in control group,the difference was not statistically significant(χ2=0.677,P>0.05).Conclusion ALA-PDT is the effective and safety method treating moderate and severe acne in clinic.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:2017-06-21。
基金项目:甘肃省自然科学基金项目(1506RJZA308)。
作者简介:宋凡君(1989-),男,在读硕士研究生。研究方向:皮肤病与性病学。
通讯作者:杨桂兰(1966-),女,主任医师,硕士生导师,医学博士,主要从事毛囊皮脂腺疾病的研究。E-mail:drgly2006@126.com
更新日期/Last Update: 1900-01-01