[1]方群英,吴丽敏,孙秀英,等.化瘀通络方联合经期抗炎或通液治疗输卵管通而不畅性不孕症临床观察[J].甘肃中医药大学学报,2018,35(05):50-54.[doi:10.16841/j.issn1003-8450.2018.05.11]
 FANG Qunying,WU Limin,SUN Xiuying,et al.Clinical observation of Huayu Tongluo Fang combined with menstrual anti-inflammatory or liquid instillation on treating fallopian tube obstruction and infertility[J].Journal of Gansu University of Chinese Medicine,2018,35(05):50-54.[doi:10.16841/j.issn1003-8450.2018.05.11]
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化瘀通络方联合经期抗炎或通液治疗输卵管通而不畅性不孕症临床观察()
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《甘肃中医药大学学报》[ISSN:1003-8450/CN:62-1062/R]

卷:
35卷
期数:
2018年05期
页码:
50-54
栏目:
临床研究与报道
出版日期:
2018-10-25

文章信息/Info

Title:
Clinical observation of Huayu Tongluo Fang combined with menstrual anti-inflammatory or liquid instillation on treating fallopian tube obstruction and infertility
作者:
方群英1 吴丽敏2 孙秀英1 乔宗惠1
1. 安徽中医药大学研究生院, 安徽 合肥 230038;
2. 中国科学技术大学附属第一医院安徽省立医院生殖中心, 安徽 合肥 230001
Author(s):
FANG Qunying1 WU Limin2 SUN Xiuying1 QIAO Zonghui1
1. Postgraduate School, Anhui University of TCM, Hefei, Anhui, 230038, China;
2. Anhui Provincial Hospital Reproductive Center, the First Affiliated Hospital of University of Science and Technology of China, Hefei, Anhui, 230001, China
关键词:
输卵管通而不畅性不孕症化瘀通络方经期抗炎输卵管通液临床疗效
Keywords:
fallopian tube obstruction and infertilityHuayu Tongluo Fangmenstrual anti-inflammatorytubal patency by liquid instillationclinical efficacy
分类号:
R271.14
DOI:
10.16841/j.issn1003-8450.2018.05.11
摘要:
目的 观察化瘀通络方联合经期抗炎或通液治疗输卵管通而不畅性不孕症的临床疗效。方法 将231例输卵管通而不畅性不孕症患者随机分为经期抗炎对照组(A组,45例)、通液对照组(B组,50例)、化瘀通络方联合经期抗炎治疗组(C组,70例)、化瘀通络方联合通液治疗组(D组,66例)4组,给予相应治疗方法治疗。1个疗程后,比较4组的临床疗效、治疗前后的中医证候积分、不良反应发生情况;随访半年,比较4组的宫内妊娠率、异位妊娠率及流产率。结果 C、D组总有效率明显高于A、B组,差异有统计学意义(P<0.05);治疗后4组中医证候积分均较同组治疗前显著降低,差异均有统计学意义(P<0.05),且C、D组降低程度明显高于A、B 2组(P<0.05);C、D组宫内妊娠率明显高于A、B组,异位妊娠率和流产率明显低于A、B组,差异均有统计学意义(P<0.05)。结论 化瘀通络方联合经期抗炎或通液治疗输卵管通而不畅性不孕症疗效显著,且安全性高,值得临床推广应用。
Abstract:
Objective To observe the clinical efficacy of Huayu Tongluo Fang combined with menstrual anti-inflammatory or liquid instillation on treating fallopian tube obstruction and infertility.Methods A total of 231 cases were randomly divided into menstrual anti-inflammatory treatment group (group A,45 cases),liquid instillation treatment group (group B,50 cases),Huayu Tongluo Fang combined with menstrual anti-inflammatory (group C,70 cases),Huayu Tongluo Fang combined with liquid instillation (group D,66 cases),each group was given corresponding treatment.After 1 course of treatment,clinical efficacy,TCM symptoms score before and after treatment,and adverse reaction occurrence of the 4 groups were compared;after half a year follow-up,the intrauterine pregnancy rate,ectopic pregnancy rate and abortion rate in the 4 groups were compared. Results The total effective rate of group C and D were significantly higher than that of group A and B,there was statistical difference (P<0.05).After treatment,TCM symptoms score of the 4 groups decreased significantly compared with the same group before treatment,there was statistical difference (P<0.05).Moreover,the decreasing degree of group C and D was significantly higher than that of group A and B (P<0.05);the rate of intrauterine pregnancy in group C and D was significantly higher than that of group A and B,while the rates of ectopic pregnancy and abortion in group C and D were significantly lower than those of group A and B.There was statistical difference (P<0.05).Conclusion Huayu Tongluo Fang combined with menstrual anti-inflammatory or liquid instillation is effective and safe on treating fallopian tube obstruction and infertility,which is worthy of clinical promotion and application.

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备注/Memo

备注/Memo:
收稿日期:2018-02-27。
基金项目:国家自然科学基金面上基金项目(81373671)。
作者简介:方群英(1991-),女,在读硕士研究生。研究方向:中医妇科学与生殖内分泌学。
通信作者:吴丽敏(1979-),女,副主任医师,医学博士。研究方向:生殖医学。E-mail:wulimin@126.com
更新日期/Last Update: 1900-01-01