[1]张博,王思农.藏药二十五味儿茶凝胶治疗肛周慢性湿疹35例临床观察[J].甘肃中医药大学学报,2018,35(05):59-61.[doi:10.16841/j.issn1003-8450.2018.05.13]
 ZHANG Bo,WANG Sinong.Clinical observation on 35 cases of perianal chronic eczema treated with Catechu Gel of Twenty-five Ingredients of Tibetan Medicine[J].Journal of Gansu University of Chinese Medicine,2018,35(05):59-61.[doi:10.16841/j.issn1003-8450.2018.05.13]
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藏药二十五味儿茶凝胶治疗肛周慢性湿疹35例临床观察()
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《甘肃中医药大学学报》[ISSN:1003-8450/CN:62-1062/R]

卷:
35卷
期数:
2018年05期
页码:
59-61
栏目:
临床研究与报道
出版日期:
2018-10-25

文章信息/Info

Title:
Clinical observation on 35 cases of perianal chronic eczema treated with Catechu Gel of Twenty-five Ingredients of Tibetan Medicine
作者:
张博1 王思农2
1. 庆阳市中医医院肛肠二科, 甘肃 庆阳 745000;
2. 甘肃中医药大学中医临床学院, 甘肃 兰州 730000
Author(s):
ZHANG Bo1 WANG Sinong2
1. The Second Anorectal Department, Qingyang TCM Hospital, Qingyang, Gansu, 745000, China;(;
2. Clinical College of TCM, Gansu University of Chinese Medicine, Lanzhou, Gansu, 730000, China
关键词:
肛周慢性湿疹藏药二十五味儿茶凝胶地奈德乳膏临床疗效
Keywords:
perianal chronic eczemaCatechu Gel of Twenty-five Ingredients of Tibetan MedicineDesonide Creamclinical efficacy
分类号:
R275.982.3
DOI:
10.16841/j.issn1003-8450.2018.05.13
摘要:
目的 观察藏药二十五味儿茶凝胶治疗肛周慢性湿疹的临床疗效。方法 将70例肛周慢性湿疹患者按照随机数字表法分为治疗组和对照组,各35例。对照组给予地奈德乳膏外涂,治疗组给予藏药二十五味儿茶凝胶外涂,2次/d。连续治疗2周后比较2组的临床症状评分及临床疗效;随访6月,比较2组患者的复发情况。结果 2组治疗后肛周瘙痒程度、皮损面积、皮损形态及渗出评分均较同组治疗前降低,差异均有统计学意义(P<0.05),且治疗组降低更显著,与对照组治疗后比较差异均有统计学意义(P<0.05);对照组总有效率为91.4%,治疗组为97.2%,2组比较差异有统计学意义(P<0.05);对照组复发率为18.5%,治疗组为9.7%,2组比较差异有统计学意义(P<0.05)。结论 藏药二十五味儿茶凝胶治疗肛周慢性湿疹疗效显著、复发率低,值得临床推广。
Abstract:
Objective To observe the clinical efficacy of Catechu Gel of Twenty-five Ingredients of Tibetan Medicine on perianal chronic eczema.Methods Seventy cases of perianal chronic eczema were divided into treatment group and control group according to random number table,35 cases in each one.The control group was smeared with Desonide Cream,while the treatment group was smeared with Catechu Gel of Twenty-five Ingredients of Tibetan Medicine,twice a day.The clinical symptom scores and clinical efficacy of the 2 groups were compared after continuous treatment for 2 weeks.The recurrence rate of two groups was compared after 6 months of follow-up.Results The score of itching degree,lesion area,lesion form and exudation score of the 2 groups both decreased compared with the same group before treatment.The difference was statistically significant(P<0.05).Moreover,the decrease was more significant in treatment group,there was significant difference compared with control group after treatment(P<0.05);the total effective rate of control group was 91.4%,that of treatment group was 97.2%,and the difference between the two groups was statistically significant (P<0.05);the recurrence rate of the control group was 18.5%,that of the treatment group was 9.7%,and the difference between the two groups was statistically significant (P<0.05).Conclusion Catechu Gel of Twenty-five Ingredients of Tibetan Medicine has significant curative effects and low recurrence rate on the treatment of perianal chronic eczema.It is worthy of clinical promotion.

参考文献/References:

[1] 中华中医药学会.中医肛肠科常见病诊疗指南[M].北京:中国中医药出版社,2012:16.
[2] 闻永,李俊,龙庆,等.耳穴联合中药坐浴及亚甲蓝封闭治疗慢性肛周湿疹55例临床观察[J].中国皮肤性病学杂志,2017,31(3):328.
[3] 郑筱萸.中药新药临床研究指导原则(试行)[M].北京:中国医药科技出版社,2002:295-299.
[4] 费颖.渗透促进剂——月桂氮酮的合成及应用研究[D].南京:南京理工大学,2006.

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[1]郑婷,朱鹏,肖静秋,等.藏药二十五味儿茶凝胶对慢性湿疹模型大鼠皮损及血清IL-4、IFN-γ含量的影响[J].甘肃中医药大学学报,2018,35(06):16.[doi:10.16841/j.issn1003-8450.2018.06.04]
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备注/Memo

备注/Memo:
收稿日期:2018-03-05。
基金项目:西北中藏药科研项目(XBXT2015-3)。
作者简介:张博(1988-),男,主治医师,医学硕士。研究方向:中医外科学。
通信作者:王思农(1966-),男,教授,医学学士。研究方向:中医药治疗皮肤病的临床及实验研究。E-mail:15095319507@163.com
更新日期/Last Update: 1900-01-01