[1]王苏丽,姚茹,周毅,等.重症胆源性胰腺炎逆行胰胆管造影术后早期经空肠营养管注入生大黄液对血清淀粉酶、C-反应蛋白及胃肠功能的影响[J].甘肃中医药大学学报,2018,35(05):77-80.[doi:10.16841/j.issn1003-8450.2018.05.18]
 WANG Suli,YAO Ru,ZHOU Yi,et al.Effects of raw Dahuang Ye on AMY,CRP and gastrointestinal function injected through jejunal feeding tube in early postoperative period of severe gallstone pancreatitis after ERCP[J].Journal of Gansu University of Chinese Medicine,2018,35(05):77-80.[doi:10.16841/j.issn1003-8450.2018.05.18]
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重症胆源性胰腺炎逆行胰胆管造影术后早期经空肠营养管注入生大黄液对血清淀粉酶、C-反应蛋白及胃肠功能的影响()
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《甘肃中医药大学学报》[ISSN:1003-8450/CN:62-1062/R]

卷:
35卷
期数:
2018年05期
页码:
77-80
栏目:
临床研究与报道
出版日期:
2018-10-25

文章信息/Info

Title:
Effects of raw Dahuang Ye on AMY,CRP and gastrointestinal function injected through jejunal feeding tube in early postoperative period of severe gallstone pancreatitis after ERCP
作者:
王苏丽 姚茹 周毅 张岁利 陈荣利
解放军第四五一医院消化内科, 陕西 西安 710054
Author(s):
WANG Suli YAO Ru ZHOU Yi ZHANG Suili CHEN Rongli
Department of Digestion, No. 451 Hospital of the PLA, Xi’an, Shaanxi, 710054, China
关键词:
重症胆源性胰腺炎逆行胰胆管造影术生大黄液C-反应蛋白血清淀粉酶胃肠功能临床观察
Keywords:
Severe gallstone pancreatitisendoscopic retrograde cholangiopancreatography(ERCP)raw Dahuang YeC-reactive protein(CRP)serum amylase (AMY)gastrointestinal functionclinical observation
分类号:
R259.76
DOI:
10.16841/j.issn1003-8450.2018.05.18
摘要:
目的 观察重症胆源性胰腺炎逆行胰胆管造影(ERCP)术后早期经空肠营养管注入生大黄液对患者血清淀粉酶(AMY)、C-反应蛋白(CRP)及胃肠功能的影响。方法 将118例重症胆源性胰腺炎患者随机分为治疗组(60例)和对照组(58例),2组均行ERCP术以解除胆道梗阻,术后均予全身综合治疗,治疗组在全身综合治疗的基础上早期经空肠营养管注入生大黄液。比较2组患者的血清AMY、胃肠功能恢复时间及CRP含量。结果 治疗组血清AMY恢复时间及胃肠功能恢复时间均明显短于对照组,2组比较差异均有统计学意义(P<0.05或P<0.01);治疗组术后48 h CRP含量明显降低,与同组术前比较差异有统计学意义(P<0.05),且治疗组降低程度明显高于对照组,2组术后48 h比较差异有统计学意义(P<0.05)。结论 早期经肠内营养管注入生大黄液能明显降低重症胆源性胰腺炎患者ERCP术后的CRP含量,缩短血清AMY及胃肠功能恢复时间,从而缩短病程,且价格低廉,值得临床推广应用。
Abstract:
Objective To observe the effects of raw Dahuang Ye on AMY,CRP and gastrointestinal function injected through the jejunal feeding tube in the early postoperative period of severe gallstone pancreatitis after ERCP.Methods A total of 118 cases with severe gallstone pancreatitis were randomly divided into treatment group(60 cases) and control group(58 cases).Both groups were performed ERCP to resolve bile duct obstruction with postoperative systemic comprehensive treatment,and the treatment group was added with raw Dahuang Ye injected through the jejunal feeding tube.The serum level of AMY recovery time,gastrointestinal function recovery time,CRP levels of the 2 groups were compared.Results Recovery time of the serum amylase level and gastrointestinal function of the treatment group was significantly shorter than that of the control group,there was statistical difference(P<0.05 or P<0.01);and CRP level at 48 h after operation in the treatment group decreased significantly,there was statistical difference compared with the same group before operation,moreover,the level of the treatment group decreased significantly higher than that of the control group,and the difference was statistically significant at 48 h after operation between the 2 groups (P<0.05).Conclusion The therapy significantly reduces CRP level,and shortens recovery time of gastrointestinal function and serum AMY.Thus,it shortens the course of disease with low price and deserves the clinical expansion and application.

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备注/Memo

备注/Memo:
收稿日期:2017-12-27。
作者简介:王苏丽(1974-),女,副主任医师,医学硕士,主要从事消化系统疾病的临床治疗工作。
更新日期/Last Update: 1900-01-01