[1]王雪利.自拟化浊降脂汤治疗痰瘀互结型高脂血症42例临床观察[J].甘肃中医药大学学报,2019,36(06):49-52.[doi:10.16841/j.issn1003-8450.2019.06.11]
 WANG Xueli.Clinical observation on 42 cases of hyperlipidemia with phlegm and blood stasis binding type treated by self-made Huazhuo Jiangzhi Tang(化浊降脂汤)[J].Journal of Gansu University of Chinese Medicine,2019,36(06):49-52.[doi:10.16841/j.issn1003-8450.2019.06.11]
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自拟化浊降脂汤治疗痰瘀互结型高脂血症42例临床观察
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《甘肃中医药大学学报》[ISSN:1003-8450/CN:62-1062/R]

卷:
36卷
期数:
2019年06期
页码:
49-52
栏目:
临床研究与报道
出版日期:
2019-12-25

文章信息/Info

Title:
Clinical observation on 42 cases of hyperlipidemia with phlegm and blood stasis binding type treated by self-made Huazhuo Jiangzhi Tang(化浊降脂汤)
作者:
王雪利
焦作市中医院消化科, 河南 焦作 454000
Author(s):
WANG Xueli
Department of Gastroenterology, Jiaozuo Hospital of Chinese Medicine, Jiaozuo, Henan, 454000, China
关键词:
高脂血症痰瘀互结型阿托伐他汀钙片化浊降脂汤血脂临床观察
Keywords:
hyperlipidemiaphlegm and blood stasis binding typeatorvastatin calcium tabletsHuazhuo Jiangzhi Tang(化浊降脂汤)blood lipidclinical observation
分类号:
R285.5
DOI:
10.16841/j.issn1003-8450.2019.06.11
摘要:
目的 观察自拟化浊降脂汤治疗痰瘀互结型高脂血症的临床疗效。方法 将84例痰瘀互结型高脂血症患者采用随机数字表法分为治疗组和对照组,各42例。治疗前,2组均给予2周的体育运动和饮食干预,在此基础上对照组给予阿托伐他汀钙片治疗,治疗组给予自拟化浊降脂汤治疗。2组均以12周为1个疗程,1个疗程后比较2组的临床疗效、不良反应发生情况及治疗前后血清总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)含量。结果 对照组总有效率为76.2%,治疗组为80.9%,2组比较差异无统计学意义(P>0.05);2组治疗后血清TC、TG、LDL-C含量均明显降低,血清HDL-C含量均明显升高,与同组治疗前比较差异有统计学意义(P<0.05),但2组治疗后以上各项指标比较差异均无统计学意义(P>0.05);对照组总不良反应发生率为26.2%,治疗组未见不良反应,2组比较差异有统计学意义(P<0.05)。结论 自拟化浊降脂汤治疗痰瘀互结型高脂血症疗效显著,与阿托伐他汀钙片疗效相当,且无明显不良反应,值得临床推广应用。
Abstract:
Objective To observe the clinical efficacy of self-made Huazhuo Jiangzhi Tang(化浊降脂汤) in the treatment of hyperlipidemia with phlegm and blood stasis binding type.Methods Eighty-four cases of hyperli- pidemia with phlegm and blood stasis binding type were divided into treatment group and control group according to random number table method,with 42 cases in each. Before treatment,the 2 groups were both given 2 weeks of sports and diet intervention,on this basis,the control group was given atorvastatin calcium tablets,while the treatment group was given self-made Huazhuo Jiangzhi Tang. Twelve weeks constituted 1 course of treatment for both groups. After 1 course of treatment,the clinical efficacy,the incidence of adverse reactions,the serum levels of total cholesterol(TC),triglyceride(TG),low density lipoprotein(LDL-C) and high density lipoprotein(HDL-C) before and after treatment in the 2 groups were compared. Results The total effective rate of the control group was 76.2%,that of the treatment group was 80.9%,and the difference between the 2 groups was not statistically significant(P>0.05). After treatment,the serum levels of TC,TG and LDL-C in the 2 groups all significantly decreased,while the serum level of HDL-C significantly increased,and the difference was statistically significant compared with the same group before treatment(P<0.05),however,there was no significant difference in the above indexes between the 2 groups after treatment(P>0.05). The total incidence of adverse reactions in the control group was 26.2%,no adverse reactions was found in the treatment group,and the difference between the 2 groups was statistically significant(P<0.05). Conclusion It has marked clinical efficacy to use self-made Huazhuo Jiangzhi Tang in the treatment of hyperlipidemia with phlegm and blood stasis binding type,which has equivalent curative effect as atorvastatin calcium tablets without marked adverse reactions. It deserves clinical promotion and application.

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备注/Memo

备注/Memo:
收稿日期:2018-12-08。
作者简介:王雪利(1978-),女,副主任中医师,医学学士。研究方向:中医内科肝、胆、脾、胃病。
更新日期/Last Update: 1900-01-01