[1]王怀泽,王峰.健肾壮骨汤联合碳酸钙D3片治疗老年骨质疏松症肝肾亏虚型40例临床观察[J].甘肃中医药大学学报,2018,35(06):61-65.[doi:10.16841/j.issn1003-8450.2018.06.13]
 WANG Huaize,WANG Feng.Clinical observation on 40 cases of senile osteoporosis with consumption of liver and kidney type treated by Jianshen Zhuanggu Tang (健肾壮骨汤) combined with calcium carbonate vitamin D3 tablets[J].Journal of Gansu University of Chinese Medicine,2018,35(06):61-65.[doi:10.16841/j.issn1003-8450.2018.06.13]
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健肾壮骨汤联合碳酸钙D3片治疗老年骨质疏松症肝肾亏虚型40例临床观察
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《甘肃中医药大学学报》[ISSN:1003-8450/CN:62-1062/R]

卷:
35卷
期数:
2018年06期
页码:
61-65
栏目:
临床研究与报道
出版日期:
2018-12-25

文章信息/Info

Title:
Clinical observation on 40 cases of senile osteoporosis with consumption of liver and kidney type treated by Jianshen Zhuanggu Tang (健肾壮骨汤) combined with calcium carbonate vitamin D3 tablets
作者:
王怀泽1 王峰2
1. 安徽中医药大学研究生院, 安徽 合肥 230038;
2. 安徽中医药大学第一附属医院骨伤科, 安徽 合肥 230031
Author(s):
WANG Huaize1 WANG Feng2
1. School of Postgraduate, Anhui University of TCM, Hefei, Anhui, 230038, China;
2. Department of Orthopedics and Traumatology, the First Affiliated Hospital of Anhui University of TCM, Hefei, Anhui, 230031, China
关键词:
老年骨质疏松症肝肾亏虚型健肾壮骨汤碳酸钙D3骨化三醇软胶囊临床观察
Keywords:
senile osteoporosis (OP)consumption of liver and kidney typeJianshen Zhuanggu Tang (健肾壮骨汤)calcium carbonate vitamin D3 tabletscalcitriol capsulesclinical observation
分类号:
R259.914.4
DOI:
10.16841/j.issn1003-8450.2018.06.13
摘要:
目的 观察健肾壮骨汤联合碳酸钙D3片治疗老年骨质疏松症(OP)肝肾亏虚型的临床疗效。方法 将80例老年OP肝肾亏虚型患者按照就诊顺序随机分为治疗组和对照组,各40例。2组患者均给予碳酸钙D3片口服,对照组在碳酸钙D3片口服的基础上联合骨化三醇软胶囊口服治疗,治疗组在碳酸钙D3片口服的基础上联合健肾壮骨汤治疗。2组均以2月为1个疗程,连续治疗3个疗程后比较2组治疗前后的视觉模拟评分法(VSA)评分、骨密度(BMD)值及中医证候积分。结果 2组治疗后VAS评分、中医证候积分均明显下降,BMD值均明显升高,与同组治疗前比较差异有统计学意义(P<0.05或P<0.01),且治疗组VAS评分、中医证候积分下降更显著,与对照组治疗后比较差异均有统计学意义(P<0.05)。结论 在碳酸钙D3片口服的基础上联合健肾壮骨汤治疗老年OP肝肾亏虚型临床疗效显著,可明显降低患者VAS评分及中医证候积分,提高患者生活质量,值得临床推广应用。
Abstract:
Objective To observe the clinical efficacy of Jianshen Zhuanggu Tang (健肾壮骨汤, JZT) combined with calcium carbonate vitamin D3 tablets in treating senile osteoporosis (OP) with consumption of liver and kidney type. Methods Eighty patients of senile OP with consumption of liver and kidney type were divided into treatment group and control group according to the visiting order, 40 cases in each one. The 2 groups were both gi-ven calcium carbonate vitamin D3 tablets orally, and the control group was added with calcitriol capsules orally, while the treatment group was added with JZT. Both groups were given a two-month course of treatment. After 3 consecutive courses of treatment, the visual analogue scores (VSA), bone mineral density (BMD) and TCM syndrome scores of the two groups were compared before and after treatment. Results After treatment, VAS scores and TCM syndrome scores of the two groups significantly decreased, while BMD value of the two groups significantly increased, which was statistically significant compared with the same group before treatment (P<0.05 or P<0.01). Moreover, VAS scores and TCM syndrome scores decreased more significantly in the treatment group, which was statistically significant compared with the control group after treatment (P<0.05). Conclusion Calcium carbonate vitamin D3 tablets combined with JZT in treating senile OP with consumption of liver and kidney type has remarkable clinical efficacy, which significantly decreases their VAS scores and TCM syndrome scores, and improves their quality life. It is worthy of clinical promotion and application.

参考文献/References:

[1] Gardner M J, Demetrakopoulos D, Shindle M K, et al.Prevention and treatment of osteoporotic fractures[J].Minerva Med, 2005, 96(5):343-352.
[2] 冯歆, 葛继荣.中医从脾论治原发性骨质疏松症的研究进展[J].中国骨质疏松杂志, 2014, 20(8):968-972.
[3] 欧阳晓俊.老年骨质疏松症——《原发性骨质疏松症诊疗指南(2017)》解读[J].实用老年医学, 2018, 32(1):95-97.
[4] 许超, 肖鲁伟, 童培建, 等.骨质疏松症的中医辨证分型客观化研究[J].中医正骨, 2010, 22(2):27-30.
[5] 韩亚军, 帖小佳, 伊力哈木·托合提.中国中老年人骨质疏松症患病率的Meta分析[J].中国组织工程研究, 2014, 18(7):1129-1134.
[6] 杜联, 殷丽平, 陈敏, 等.补肾壮骨胶囊对糖尿病骨质疏松症骨代谢及股骨生物力学相关指标的影响[J].甘肃中医学院学报, 2010, 27(3):18-20.
[7] 梁文娜, 李西海, 李灿东.绝经后骨质疏松的核心病机——骨痿[J].中国老年学杂志, 2015, 35(18):5333-5335.
[8] 王国柱, 张平安, 孙超.抗疏强骨方治疗肝肾亏虚型原发性骨质疏松症临床观察[J].陕西中医, 2016, 37(10):1362-1363.
[9] 潘赐明, 周丽红, 赵黎.新安医家王乐匋学术特色浅谈[J].湖北民族学院学报(医学版), 2017, 34(3):48-49.
[10] Chia L C, Che S L, Guia H L.Phytochemical characteristics free radical scavenging activities, and neuroprotection of five medicinal plant extracts[J].Evid Based Complement Alternat Med, 2012, 2012:984295.
[11] 魏国俊, 丁玉芬, 董林, 等.中医药治疗绝经后骨质疏松症的研究进展[J].甘肃中医药大学学报, 2017, 34(5):82-85.

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备注/Memo

备注/Memo:
收稿日期:2018-03-04。
作者简介:王怀泽(1992-),男,在读硕士研究生。研究方向:中医骨伤科学。
通信作者:王峰(1961-),男,主任中医师,教授,医学学士,主要从事中医药防治骨伤科颈肩腰腿痛及骨关节疾病的研究。E-mail:gu08@sina.com
更新日期/Last Update: 1900-01-01