[1]周正新,刘安平,王峰,等.骨蚀宁I号治疗股骨头缺血性坏死瘀血期90例临床观察[J].甘肃中医药大学学报,2019,36(01):48-51.[doi:10.16841/j.issn1003-8450.2019.01.10]
 ZHOU Zhengxin,LIU Anping,WANG Feng,et al.Clinical observation on 90 cases of ischemic necrosis of femoral head in blood stasis period treated by Gushining I(骨蚀宁I号)[J].Journal of Gansu University of Chinese Medicine,2019,36(01):48-51.[doi:10.16841/j.issn1003-8450.2019.01.10]
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骨蚀宁I号治疗股骨头缺血性坏死瘀血期90例临床观察
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《甘肃中医药大学学报》[ISSN:1003-8450/CN:62-1062/R]

卷:
36卷
期数:
2019年01期
页码:
48-51
栏目:
临床研究与报道
出版日期:
2019-02-25

文章信息/Info

Title:
Clinical observation on 90 cases of ischemic necrosis of femoral head in blood stasis period treated by Gushining I(骨蚀宁I号)
作者:
周正新 刘安平 王峰 张建华 李文华 王正 朱磊
安徽中医药大学第一附属医院骨伤科, 安徽 合肥 230031
Author(s):
ZHOU Zhengxin LIU Anping WANG Feng ZHANG Jianhua LI Wenhua WANG Zheng ZHU Lei
Department of Orthopedics and Traumatology, the First Affiliated Hospital of Anhui University of TCM, Hefei, Anhui, 230031, China
关键词:
股骨头缺血性坏死瘀血期骨蚀宁I号仙灵骨葆胶囊临床观察
Keywords:
ischemic necrosis of femoral head(INFH)blood stasis periodGushining I(骨蚀宁I号)Xianling Gubao Jiaonang(仙灵骨葆胶囊)clinical observation
分类号:
R274.918
DOI:
10.16841/j.issn1003-8450.2019.01.10
摘要:
目的 观察骨蚀宁I号治疗股骨头缺血性坏死(INFH)瘀血期的临床疗效。方法 将120例INFH瘀血期患者随机分为对照组(30例)和治疗组(90例)。对照组采用仙灵骨葆胶囊治疗,治疗组采用骨蚀宁Ⅰ号治疗。1年为1个疗程,2个疗程后比较2组的临床疗效,6月后比较2组治疗前后低密度脂蛋白(LDL)、总胆固醇(TC)、甘油三酯(TG)含量。结果 对照组总有效率为92.9%,治疗组为94.3%,2组比较差异无统计学意义(P>0.05);治疗后治疗组LDL、TC、TG含量均明显降低,与同组治疗前比较差异有统计学意义(P<0.05),且治疗后治疗组TG水平明显低于对照组,2组比较差异有统计学意义(P<0.05)。结论 骨蚀宁Ⅰ号治疗INFH瘀血期疗效确切,可明显降低患者LDL、TC、TG含量,值得临床推广应用。
Abstract:
Objective To observe the clinical efficacy of Gushining I(骨蚀宁I号) in the treatment of ischemic necrosis of femoral head(INFH). Methods A total of 120 patients with INFH in blood stasis period were randomly divided into control group(30 cases) and treatment group(90 cases). The control group was given Xianling Gubao Jiaonang(仙灵骨葆胶囊),while the treatment group was given Gushining I. One year constituted a course of treatment. The clinical efficacy of the 2 groups was compared after 2 courses,the levels of low density lipoprotein(LDL),total cholesterol(TC),and triglyceride(TG) of the 2 groups before and after treatment after 6 months were compared. Results The total effective rate of the control group was 92.9%,that of the treatment group was 94.3%,there was no statistically significant difference between the two groups(P>0.05). After treatment,the levels of LDL,TC and TG all decreased significantly in the treatment group,there was statistically significant difference compared with the same group before treatment(P<0.05),moreover,the level of TG in the treatment group was significantly lower than that of the control group after treatment,there was statistically significant difference between the two groups(P<0.05). Conclusion It has significant clinical efficacy to use Gushining I in the treatment of INFH in blood stasis period,which can markedly decrease the levels of LDL,TC and TG of the patients. It deserves clinical promotion and application.

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备注/Memo

备注/Memo:
收稿日期:2018-03-15。
基金项目:安徽省科技攻关项目(08010302186)。
作者简介:周正新(1968-),男,主任医师,硕士生导师,医学博士,主要从事骨与关节疾病的中西医结合治疗及研究。
更新日期/Last Update: 1900-01-01