[1]吴冠楠,孟财周,张定华.针刺联合桃红四物汤治疗糖尿病周围神经病变随机对照研究[J].甘肃中医药大学学报,2019,36(01):64-67.[doi:10.16841/j.issn1003-8450.2019.01.14]
 WU Guannan,MENG Caizhou,ZHANG Dinghua.A randomized controlled trial of acupuncture combined with Taohong Siwu Tang(桃红四物汤) in the treatment of diabetic peripheral neuropathy[J].Journal of Gansu University of Chinese Medicine,2019,36(01):64-67.[doi:10.16841/j.issn1003-8450.2019.01.14]
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针刺联合桃红四物汤治疗糖尿病周围神经病变随机对照研究
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《甘肃中医药大学学报》[ISSN:1003-8450/CN:62-1062/R]

卷:
36卷
期数:
2019年01期
页码:
64-67
栏目:
针灸推拿
出版日期:
2019-02-25

文章信息/Info

Title:
A randomized controlled trial of acupuncture combined with Taohong Siwu Tang(桃红四物汤) in the treatment of diabetic peripheral neuropathy
作者:
吴冠楠1 孟财周2 张定华3
1. 甘肃中医药大学中医临床学院, 甘肃 兰州 730000;
2. 中宁县中医医院针灸推拿科, 宁夏 中宁 755100;
3. 甘肃省中医院内分泌科, 甘肃 兰州 730000
Author(s):
WU Guannan1 MENG Caizhou2 ZHANG Dinghua3
1. Clinical College of TCM, Gansu University of Chinese Medicine, Lanzhou, Gansu, 730000, China;
2. Department of Acupuncture and Massage, Zhongning Hospital of TCM, Zhongning, Ningxia, 755100, China;
3. Department of Endocrinology, Gansu Hospital of TCM, Lanzhou, Gansu, 730000, China
关键词:
糖尿病周围神经病变针刺桃红四物汤依帕司他片神经传导速度中医证候积分临床疗效
Keywords:
diabetic peripheral neuropathy(DPN)acupunctureTaohong Siwu Tang(桃红四物汤)ipastar tabletthe conduction velocity of nerveTCM symptom scoresclinical efficacy
分类号:
R246.6
DOI:
10.16841/j.issn1003-8450.2019.01.14
摘要:
目的 观察针刺联合桃红四物汤治疗糖尿病周围神经病变的临床疗效。方法 将90例糖尿病周围神经病变患者采用随机数字表法分为对照组、治疗组1和治疗组2,各30例。3组均给予基础治疗,同时对照组予依帕司他片口服,治疗组1予桃红四物汤口服,治疗组2予针刺联合桃红四物汤口服,3组均以2周为1个疗程,治疗2个疗程后比较3组的临床疗效,治疗前后腓总神经、正中神经的传导速度,中医证候积分。结果 对照组、治疗组1、治疗组2的总有效率分别为53.33%,73.33%,96.67%,3组组间比较差异均有统计学意义(P<0.05);治疗后3组腓总神经、正中神经的传导速度均较同组治疗前明显加快,中医证候积分均较同组治疗前明显降低,差异有统计学意义(P<0.05),且治疗组1、治疗组2对各项指标的改善作用明显优于对照组(P<0.05),治疗组2对各项指标的改善作用明显优于治疗组1(P<0.05)。结论 针刺联合桃红四物汤既能改善糖尿病周围神经病变患者的临床症状,又能提高腓总神经和正中神经的传导速度,疗效显著,且无明显不良反应,值得临床推广应用。
Abstract:
Objective To observe the clinical efficacy of acupuncture combined with Taohong Siwu Tang(桃红四物汤) in the treatment of diabetic peripheral neuropathy(DPN). Methods Ninety patients of DPN were divided into control group,treatment group 1 and treatment group 2 according to random number table,with 30 cases in each. The 3 groups were all given basic treatment,meanwhile the control group was given ipastar tablets orally,the treatment group 1 was given Taohong Siwu Tang orally,the treatment group 2 was given acupuncture combined with Taohong Siwu Tang. A course of treatment was 2 weeks for 3 groups. After 2 courses of treatment,the clinical efficacy,the conduction velocity of common peroneal nerve and median nerve before and after treatment,TCM symptom scores of the 3 groups were compared. Results The total effective rates of the control group,the treatment group 1 and the treatment group 2 were 53.33%,73.33% and 96.67%,respectively,there were statistically significant differences among the three groups(P<0.05). The conduction velocity of common peroneal nerve and median nerve of the 3 groups after treatment was significantly faster than that of the same group before treatment,TCM symptom scores were all significantly lower than those of the same group before treatment,there were statistically significant differences(P<0.05).And the treatment group 1 and the treatment group 2 had significant improvement in all indicators than the control group(P<0.05),the treatment group 2 had significant improvement in all indicators than the treatment group 1(P<0.05). Conclusion Acupuncture combined with Taohong Siwu Tang in the treatment of patients with DPN not only improves the clinical symptoms,but also increases the conduction velocity of common peroneal nerve and median nerve,with significant clinical efficacy and very few noticeable adverse reactions,which deserves clinical promotion and application.

参考文献/References:

[1] 廉羚.2型糖尿病周围神经病变的诊治进展[J].中国医学工程,2015,23(2):197-198.
[2] 聂发传,石英.糖尿病周围神经病变发生机制研究进展[J].重庆医学,2015,44(1):122-125.
[3] 中华医学会糖尿病学分会.中国2型糖尿病防治指南(2013年版)[M].北京:北京大学医学出版社,2014:5,37.
[4] 郑筱萸.中药新药临床研究指导原则(试行)[M].北京:中国医药科技出版社,2002:233-237.
[5] 肖红胜,韩建新.中西医结合疗法在糖尿病周围神经病变中的应用效果研究[J].中国中医基础医学杂志,2014,20(8):1094-1095.
[6] 方朝晖.中西医结合内分泌代谢疾病诊治学[M].北京:中国中医药出版社,2013:345.
[7] 王茂源,刘国安,吕鹏强.针刺联合补阳还五汤治疗糖尿病周围神经病变30例临床观察[J].甘肃中医药大学学报,2016,33(6):69-71.
[8] 王茂源,吴海娟,郭腾飞.中医药治疗糖尿病周围神经病变临床研究进展[J].甘肃中医药大学学报,2016,33(2):83-85.
[9] 柴海兰.桃红四物汤与针刺联合西药治疗糖尿病周围神经病变随机平行对照研究[J].实用中医内科杂志,2014,28(11):154-156.
[10] 俞锦芳,崔之础.针刺治疗糖尿病性周围神经病变临床研究[J].中国针灸,2000,20(4):203-204.

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备注/Memo

备注/Memo:
收稿日期:2018-06-06。
作者简介:吴冠楠(1992-),男,在读硕士研究生。研究方向:糖尿病及并发症的中医药防治。
通信作者:张定华(1964-),女,主任医师,硕士生导师,医学学士,主要从事中医药防治内分泌疾病的相关研究。E-mail:Zhangdinghua2010@sina.com
更新日期/Last Update: 1900-01-01