[1]区作明,李兰,田浩,等.加味骨宝汤联合钙剂治疗绝经后骨质疏松症肝肾不足证38例临床观察[J].甘肃中医药大学学报,2019,36(03):63-66.[doi:10.16841/j.issn1003-8450.2019.03.14]
 OU Zuoming,LI Lan,TIAN Hao,et al.Clinical observation on 38 cases of postmenopausal osteoporosis with liver and kidney deficiency syndrome treated by Jiawei Gubao Tang(加味骨宝汤) combined with calcium[J].Journal of Gansu University of Chinese Medicine,2019,36(03):63-66.[doi:10.16841/j.issn1003-8450.2019.03.14]
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加味骨宝汤联合钙剂治疗绝经后骨质疏松症肝肾不足证38例临床观察()
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《甘肃中医药大学学报》[ISSN:1003-8450/CN:62-1062/R]

卷:
36卷
期数:
2019年03期
页码:
63-66
栏目:
临床研究与报道
出版日期:
2019-06-25

文章信息/Info

Title:
Clinical observation on 38 cases of postmenopausal osteoporosis with liver and kidney deficiency syndrome treated by Jiawei Gubao Tang(加味骨宝汤) combined with calcium
作者:
区作明1 李兰2 田浩1 陈一鸣1
1. 佛山市高明区中医院骨科, 广东 佛山 528500;
2. 佛山市中医院骨科, 广东 佛山 528000
Author(s):
OU Zuoming1 LI Lan2 TIAN Hao1 CHEN Yiming1
1. Department of Orthopedics, Foshan City Gaoming District Hospital of Chinese Medicine, Foshan, Guangdong, 528500, China;
2. Department of Orthopedics, Foshan Municipal Hospital of Chinese Medicine, Foshan, Guangdong, 528000, China
关键词:
绝经后骨质疏松症肝肾不足证加味骨宝汤鲑鱼降钙素鼻喷剂视觉模拟评分法评分骨密度血清骨碱性磷酸酶临床疗效
Keywords:
postmenopausal osteoporosisliver and kidney deficiency syndromeJiawei Gubao Tang(加味骨宝汤)salmon calcitonin nasal spray agentvisual analogue score(VAS)bone mineral densityserum bone alkaline phosphatase(BALP)clinical efficacy
分类号:
R271.11+5
DOI:
10.16841/j.issn1003-8450.2019.03.14
摘要:
目的 观察加味骨宝汤联合钙剂治疗绝经后骨质疏松症肝肾不足证的临床疗效。方法 将76例绝经后骨质疏松症肝肾不足证患者采用随机数字表法分为治疗组和对照组,各38例。2组均口服钙剂,在此基础上,治疗组口服加味骨宝汤,对照组采用鲑鱼降钙素鼻喷剂喷鼻治疗。比较2组的临床疗效及治疗前后的视觉模拟评分法(VAS)评分、L2~4正位骨密度及血清骨碱性磷酸酶(BALP)水平。结果 治疗组总有效率为94.74%,对照组为84.21%,2组比较差异无统计学意义(P>0.05);治疗后2组VAS评分及血清BALP水平均明显降低,L2~4正位骨密度均明显升高,与同组治疗前比较差异有统计学意义(P<0.05),2组治疗后各项指标比较差异均无统计学意义(P>0.05)。结论 加味骨宝汤联合钙剂治疗绝经后骨质疏松症肝肾不足证能明显缓解患者腰背部疼痛、增加骨密度、降低血清BALP水平,疗效确切,虽与鲑鱼降钙素鼻喷剂疗效相当,但可避免致癌风险,且价格相对低廉,能替代鲑鱼降钙素鼻喷剂在临床中使用。
Abstract:
Objective To observe the clinical efficacy of Jiawei Gubao Tang(加味骨宝汤) combined with calcium in the treatment of postmenopausal osteoporosis with liver and kidney deficiency syndrome.Methods Se- venty-six cases of postmenopausal osteoporosis with liver and kidney deficiency syndrome were divided into treatment group and control group according to random number table method, with 38 cases in each. Both groups took calcium orally. On this basis, the treatment group took Jiawei Gubao Tang orally, while the control group was given nasal spray with salmon calcitonin nasal spray agent. The clinical efficacy, visual analogue score(VAS), L2~4 orthophoric bone mineral density and serum bone alkaline phosphatase(BALP) levels between the two groups before and after treatment were compared.Results The total effective rate of the treatment group was 94.74%,that of the control group was 84.21%,and there was no statistically significant difference between the two groups(P>0.05).After treatment,the VAS scores and serum BALP levels of the two groups all significantly decreased,L2~4 orthophoric bone mineral density increased significantly,there was statistically significant difference compared with the same group before treatment(P<0.05).After treatment,there was no statistically significant difference in each index between the two groups(P>0.05).Conclusion Jiawei Gubao Tang combined with calcium in the treatment of postmenopausal osteoporosis with liver and kidney deficiency syndrome can significantly alleviate back pain,increase bone mineral density and reduce the level of serum BALP,with exact curative effect.Although the curative effect is similar to that of salmon calcitonin nasal spray agent,it can avoid the risk of carcinogenesis, and the price is relatively low.It can replace salmon calcitonin nasal spray agent in clinical use.

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备注/Memo

备注/Memo:
收稿日期:2018-03-10。
基金项目:2017年度佛山市卫生和计划生育局医学科研项目(20170409)。
作者简介:区作明(1983-),男,主治中医师,在读博士研究生。研究方向:骨与关节损伤的治疗和康复以及骨质疏松症的临床治疗。
更新日期/Last Update: 1900-01-01